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Anti-CXCL13/BCA-1 Antibody (6I514)

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产品编号 TMAY-03664

Anti-CXCL13/BCA-1 Antibody (6I514) 是一种 Mouse 抗体,靶向 CXCL13/BCA-1。Anti-CXCL13/BCA-1 Antibody (6I514) 可用于 ELISA。

Anti-CXCL13/BCA-1 Antibody (6I514)

Anti-CXCL13/BCA-1 Antibody (6I514)

Rating icon 还可以
产品编号 TMAY-03664

Anti-CXCL13/BCA-1 Antibody (6I514) 是一种 Mouse 抗体,靶向 CXCL13/BCA-1。Anti-CXCL13/BCA-1 Antibody (6I514) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-CXCL13/BCA-1 Antibody (6I514) is a Mouse antibody targeting CXCL13/BCA-1. Anti-CXCL13/BCA-1 Antibody (6I514) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG1
克隆号
6I514
交叉反应
Canine
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Canine BCA-1 / CXCL13 ( TMPY-03708; XP_851619.3; Val23-Asn110). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The chemokine CXCL13, also known as BCA-1 (B-cell-attracting chemokine-1) or BLC (B-lymphocyte chemoattractant), which belongs to the CXC chemokine family. CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues. CXCL13 is known to dictate homing and motility of B cells in lymphoid tissue and has been implicated in the formation of ectopic lymphoid tissue in chronic inflammation. It involves in B-cell compartmental homing within secondary lymphoid organs and recently implicated in the pathogenesis of inflammatory and malignant lymphocyte-mediated diseases. In Primary central nervous system lymphoma (PCNSL), expression of BCA-1 by malignant lymphocytes and vascular endothelium may influence tumor development and localization to central nervous system (CNS). In T-lymphocytes, CXCL13 expression is thought to reflect a germinal center origin of the T-cell. CXCL13 expression may also provide an additional useful tool for the diagnosis of Angioimmunoblastic T-cell lymphoma (AITL).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Canine BCA-1 / CXCL13 Protein (TMPY-03708)
抗原种属
Canine
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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