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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DcR3 Polyclonal Antibody

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货号 TMAB-05014

Anti-DcR3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DcR3。Anti-DcR3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-DcR3 Polyclonal Antibody

Anti-DcR3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05014

Anti-DcR3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DcR3。Anti-DcR3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-DcR3 Polyclonal Antibody is a Rabbit antibody targeting DcR3. Anti-DcR3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Dog,Cow,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1and DcR2, DcR3 is a soluble rather than a membraneassociated molecule. DcR3 binds to FasL and LIGHT andinhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and coloncarcinomas and in some normal tissues.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DcR3
抗原种属
Human
基因名称
TNFRSF6B
基因ID
8771
蛋白名称
Tumor necrosis factor receptor superfamily member 6B
Uniprot ID
O95407
功能
Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.
化学信息
分子量Theoretical: 30 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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