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Anti-DKC1 Antibody (3S961)

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货号 TMAB-05174

Anti-DKC1 Antibody (3S961) 是一种 Rabbit 抗体,靶向 DKC1。Anti-DKC1 Antibody (3S961) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-DKC1 Antibody (3S961)

Anti-DKC1 Antibody (3S961)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05174

Anti-DKC1 Antibody (3S961) 是一种 Rabbit 抗体,靶向 DKC1。Anti-DKC1 Antibody (3S961) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-DKC1 Antibody (3S961) is a Rabbit antibody targeting DKC1. Anti-DKC1 Antibody (3S961) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
3S961
反应种属
Human,Mouse (predicted:Rat)
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm and Nucleus, nucleolus. Nucleus, Cajal body. Also localized to Cajal bodies.
组织特异性Ubiquitously expressed.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Isoform 1: Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. Isoform 3: Promotes cell to cell and cell to substratum adhesion, increases the cell proliferation rate and leads to cytokeratin hyper-expression.
抗原信息
免疫原
A synthesized peptide: human Dyskerin
抗原种属
Human
基因名称
DKC1
基因ID
蛋白名称
H/ACA ribonucleoprotein complex subunit DKC1
Uniprot ID
功能
Isoform 1: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
化学信息
分子量Theoretical: 58 kDa. Actual: 58 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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