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Anti-DKC1 Antibody (3S961) 是一种 Rabbit 抗体,靶向 DKC1。Anti-DKC1 Antibody (3S961) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
Anti-DKC1 Antibody (3S961) 是一种 Rabbit 抗体,靶向 DKC1。Anti-DKC1 Antibody (3S961) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-DKC1 Antibody (3S961) is a Rabbit antibody targeting DKC1. Anti-DKC1 Antibody (3S961) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| 克隆号 | 3S961 |
| 反应种属 | Human,Mouse (predicted:Rat) |
| 应用 | WBIHC-PIHC-FrICC/IFIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm and Nucleus, nucleolus. Nucleus, Cajal body. Also localized to Cajal bodies. |
| 组织特异性 | Ubiquitously expressed. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Isoform 1: Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. Isoform 3: Promotes cell to cell and cell to substratum adhesion, increases the cell proliferation rate and leads to cytokeratin hyper-expression. |
| 免疫原 | A synthesized peptide: human Dyskerin |
| 抗原种属 | Human |
| 基因名称 | DKC1 |
| 基因ID | |
| 蛋白名称 | H/ACA ribonucleoprotein complex subunit DKC1 |
| Uniprot ID | |
| 功能 | Isoform 1: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. |
| 分子量 | Theoretical: 58 kDa. Actual: 58 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |