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别名 抗小鼠 IL-6 抗体 (MP5-20F3)
Anti-Mouse IL-6 Antibody (MP5-20F3)是抗小鼠IL-6的单克隆抗体,可通过阻断IL-6重塑肿瘤微环境,同时抑制STAT3通路并增强T细胞浸润,适用于炎症及感染疾病(如恶性胸腔积液,MPE)的相关研究。
Anti-Mouse IL-6 Antibody (MP5-20F3)是抗小鼠IL-6的单克隆抗体,可通过阻断IL-6重塑肿瘤微环境,同时抑制STAT3通路并增强T细胞浸润,适用于炎症及感染疾病(如恶性胸腔积液,MPE)的相关研究。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 1,780 | 2-4周 | |
| 5 mg | ¥ 5,980 | 2-4周 | |
| 10 mg | 待询 | 2-4周 |
| 产品描述 | Anti-Mouse IL-6 Antibody (MP5-20F3) is a monoclonal antibody against mouse IL-6, which can reshape the tumor microenvironment by blocking IL-6, inhibit the STAT3 pathway and enhance T cell infiltration, and is suitable for research on inflammatory and infectious diseases (such as malignant pleural effusion, MPE). |
| 体内活性 | Anti-Mouse IL-6 Antibody (MP5-20F3) 以200 μg剂量腹腔注射(第7天和第14天给药),可显著减少携带Lewis肺癌(LLC)肿瘤的雄性C57BL/6J小鼠的恶性胸腔积液(MPE)体积,延长其存活时间,并增强CD8+ T细胞浸润[1]。 |
| 别名 | 抗小鼠 IL-6 抗体 (MP5-20F3) |
| 克隆号 | MP5-20F3 |
| 反应种属 | Mouse |
| 应用 | ELISA FCM Functional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | Rat IgG1 kappa |
| 推荐同型对照 |
| 偶联 | Unconjugated |
| 基因ID | |
| Uniprot ID | |
| 靶点 | IL-6 |
| 分子量 | 150 kDa |
| 存储 | store at low temperature | store at -20°C | Shipping with blue ice. |
对于不同动物的给药剂量换算,您也可以参考 更多