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Anti-Phospho-TYK2 (Tyr1054) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-TYK2 (Tyr1054)。Anti-Phospho-TYK2 (Tyr1054) Polyclonal Antibody 可用于 WB。
Anti-Phospho-TYK2 (Tyr1054) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-TYK2 (Tyr1054)。Anti-Phospho-TYK2 (Tyr1054) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-TYK2 (Tyr1054) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TYK2 (Tyr1054). Anti-Phospho-TYK2 (Tyr1054) Polyclonal Antibody can be used in WB. |
别名 | Tyk2 (p-Y1054), Tyk2 (p-Tyr1054), TYK2, p-Tyk2 (Y1054), p-Tyk2 (Tyr1054), Non-receptor tyrosine-protein kinase TYK2 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from HT29 cells untreated (lane 1) or treated with Anisomycin (lane 2) using TYK2 (Phospho-Tyr1054) Antibody TMAC-04173. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of tyrosine 1054 (H-E-Y(p)-Y-R) derived from Human TYK2 |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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