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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NFX1 Polyclonal Antibody

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货号 TMAB-09451

Anti-NFX1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NFX1。Anti-NFX1 Polyclonal Antibody 可用于 WB。

Anti-NFX1 Polyclonal Antibody

Anti-NFX1 Polyclonal Antibody

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货号 TMAB-09451

Anti-NFX1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NFX1。Anti-NFX1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-NFX1 Polyclonal Antibody is a Rabbit antibody targeting NFX1. Anti-NFX1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. It may play a role in the inflammatory response, regulating its duration by limiting the period in which class II MHC molecules are induced by IFN gamma. The RING type zinc finger domain interacts with an ubiquitin conjugating enzyme (E2) and facilitates ubiquitination.
抗原信息
免疫原
KLH conjugated synthetic peptide: human NFX1
抗原种属
Human
基因名称
NFX1
基因ID
4799
蛋白名称
Transcriptional repressor NF-X1
Uniprot ID
Q12986
功能
Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
化学信息
分子量Theoretical: 124 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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