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CD19 Protein, Mouse, Recombinant (hFc)

产品编号 TMPY-07198

CD19 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P25918.

CD19 Protein, Mouse, Recombinant (hFc)

CD19 Protein, Mouse, Recombinant (hFc)

产品编号 TMPY-07198
CD19 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P25918.
规格价格库存数量
100 μg
¥ 4,460
期货
1 mg 待询 期货
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产品信息

生物活性
Immobilized Recombinant Mouse CD19 Protein (Fc Tag) at 2 μg/mL (100 μL/well) can bind CD19 Antibody, Rabbit MAb, the EC50 is 30-100 ng/mL.
产品描述
CD19 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P25918.
种属
Mouse
表达系统
HEK293 Cells
标签C-His
蛋白编号P25918
别名
Cd19
蛋白构建
A DNA sequence encoding the Mouse CD19 (NP_033974.2) (Arg19-Gly287) was expressed with a hFc tag at the C-terminus.
蛋白纯度
≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
分子量56.3 kDa (predicted); 131.9 kDa (reducing contition)
内毒素< 1.0 EU per μg protein as determined by the LAL method.
缓冲液Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
复溶方法
Please refer to the lot-specific COA.
存储
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice.
研究背景
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in the threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell co-receptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

参考文献

SCI 文献

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

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