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Anti-BAFFR/TNFRSF13C Antibody (2H990) 是一种 Mouse 抗体,靶向 BAFFR/TNFRSF13C。Anti-BAFFR/TNFRSF13C Antibody (2H990) 可用于 ELISA。
Anti-BAFFR/TNFRSF13C Antibody (2H990) 是一种 Mouse 抗体,靶向 BAFFR/TNFRSF13C。Anti-BAFFR/TNFRSF13C Antibody (2H990) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μL | ¥ 1,689 | 5日内发货 |
产品描述 | Anti-BAFFR/TNFRSF13C Antibody (2H990) is a Mouse antibody targeting BAFFR/TNFRSF13C. Anti-BAFFR/TNFRSF13C Antibody (2H990) can be used in ELISA. |
别名 | tumor necrosis factor receptor superfamily, member 13C, prolixin, CVID4, CD268, BROMIX, BAFF-R, BAFFR |
Ig Type | Mouse IgG1 |
克隆号 | 2H990 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BAFFR/TNFRSF13C (rh BAFFR/TNFRSF13C; TMPY-05060; NP_443177.1; Arg2-Ala71). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. A tumor necrosis factor receptor (TNFR), or death receptor, is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. It has been proposed that abnormally high levels of BAFFR/TNFRSF13C (CD268) may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: Human BAFFR/TNFRSF13C Protein (TMPY-05060) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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