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Anti-GCHFR Polyclonal Antibody

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货号 TMAB-06383

Anti-GCHFR Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GCHFR。Anti-GCHFR Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-GCHFR Polyclonal Antibody

Anti-GCHFR Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06383

Anti-GCHFR Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GCHFR。Anti-GCHFR Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-GCHFR Polyclonal Antibody is a Rabbit antibody targeting GCHFR. Anti-GCHFR Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Pig,Cow)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Nucleus membrane. Cytoplasm; cytosol.
组织特异性In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level).
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. The molecular weight of GFRP is approximately 9.5kDa although cross-linking experiments have shown that GFRP is usually found as a homodimer or as a pentamer. 15q15.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GCHFR
抗原种属
Human
基因名称
GCHFR
基因ID
蛋白名称
GTP cyclohydrolase 1 feedback regulatory protein
Uniprot ID
功能
Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.
化学信息
分子量Theoretical: 10 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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