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Anti-Natriuretic Peptide Receptor A Polyclonal Antibody

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货号 TMAB-09253

Anti-Natriuretic Peptide Receptor A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Natriuretic Peptide Receptor A。Anti-Natriuretic Peptide Receptor A Polyclonal Antibody 可用于 WB。

Anti-Natriuretic Peptide Receptor A Polyclonal Antibody

Anti-Natriuretic Peptide Receptor A Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09253

Anti-Natriuretic Peptide Receptor A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Natriuretic Peptide Receptor A。Anti-Natriuretic Peptide Receptor A Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Natriuretic Peptide Receptor A Polyclonal Antibody is a Rabbit antibody targeting Natriuretic Peptide Receptor A. Anti-Natriuretic Peptide Receptor A Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM, May 2009]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Natriuretic Peptide Receptor A
抗原种属
Human
基因名称
NPR1
基因ID
4881
蛋白名称
Atrial natriuretic peptide receptor 1
Uniprot ID
P16066
功能
Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
化学信息
分子量Theoretical: 113 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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