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Anti-Phospho-Period Circadian Protein 2 (Ser662) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Period Circadian Protein 2 (Ser662)。Anti-Phospho-Period Circadian Protein 2 (Ser662) Polyclonal Antibody 可用于 WB,IHC。
Anti-Phospho-Period Circadian Protein 2 (Ser662) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Period Circadian Protein 2 (Ser662)。Anti-Phospho-Period Circadian Protein 2 (Ser662) Polyclonal Antibody 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-Period Circadian Protein 2 (Ser662) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Period Circadian Protein 2 (Ser662). Anti-Phospho-Period Circadian Protein 2 (Ser662) Polyclonal Antibody can be used in WB,IHC. |
别名 | p-Period Circadian Protein 2 (Ser662), p-Period Circadian Protein 2 (S662), Period Circadian Protein 2 (p-Ser662), Period Circadian Protein 2 (p-S662) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of extracts from 3T3 cells, treated with PMA (125ng/ml, 30mins), using Period Circadian Protein 2 (Phospho-Ser662) antibody TMAC-03158. The lane on the right is treated with the synthesized peptide. 2. Western blot analysis of extracts from 3T3, HeLa and K562 cells, using Period Circadian Protein 2 (Phospho-Ser662) Antibody TMAC-03158. The lane on the left is treated with synthesized peptide. 3. Immunohistochemistry analysis of paraffin-embedded human brain tissue using Period Circadian Protein 2 (Phospho-Ser662) antibody TMAC-03158. The picture on the right is treated with the synthesized peptide. |
应用 | |
推荐剂量 | WB: 1:500-3000; IHC: 1:50-100 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers'). |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 662 (A-E-S(p)-V-A) derived from Human Period Circadian Protein 2 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 120 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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