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Anti-Cathepsin K Polyclonal Antibody

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产品编号 TMAB-00298

别名 CTSO2, CTSO, CTSK, Cathepsin X, Cathepsin O2, Cathepsin O, Cathepsin K

Anti-Cathepsin K Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Cathepsin K。Anti-Cathepsin K Polyclonal Antibody 可用于 IF,IHC-Fr,WB。

Anti-Cathepsin K Polyclonal Antibody

Anti-Cathepsin K Polyclonal Antibody

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产品编号 TMAB-00298 别名 CTSO2, CTSO, CTSK, Cathepsin X, Cathepsin O2, Cathepsin O, Cathepsin K

Anti-Cathepsin K Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Cathepsin K。Anti-Cathepsin K Polyclonal Antibody 可用于 IF,IHC-Fr,WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Cathepsin K Polyclonal Antibody is a Rabbit antibody targeting Cathepsin K. Anti-Cathepsin K Polyclonal Antibody can be used in IF,IHC-Fr,WB.
别名CTSO2, CTSO, CTSK, Cathepsin X, Cathepsin O2, Cathepsin O, Cathepsin K
Ig Type
IgG
交叉反应
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,GuineaPig)
验证活性
Sample:
Lane 1: Mouse Raw264.7 cell lysates
Lane 2: Mouse 4T1 cell lysates
Primary: Anti-Cathepsin K (TMAB-00298) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 36 kDa
Observed band size: 46 kDa
verifiedActivity
应用IFIHC-FrWB
推荐剂量
WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Lysosome.
组织特异性Tissue specificityPredominantly expressed in osteclasts (bones).
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Cathepsin K
抗原种属
Human
基因名称
CTSK
基因ID
蛋白名称
Cathepsin K
Uniprot ID
功能
Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation.
化学信息
分子量Theoretical: 36 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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