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Anti-Oct4 Antibody (5L999)

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货号 TMAB-09745

Anti-Oct4 Antibody (5L999) 是一种 Rabbit 抗体,靶向 Oct4。Anti-Oct4 Antibody (5L999) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Oct4 Antibody (5L999)

Anti-Oct4 Antibody (5L999)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09745

Anti-Oct4 Antibody (5L999) 是一种 Rabbit 抗体,靶向 Oct4。Anti-Oct4 Antibody (5L999) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-Oct4 Antibody (5L999) is a Rabbit antibody targeting Oct4. Anti-Oct4 Antibody (5L999) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
5L999
反应种属
Human (predicted:Mouse)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.Note=Expressed in a diffuse and slightly punctuate pattern.
组织特异性Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
浓度1mg/ml
研究背景Expression of the POU-domain transcription factor Octamer-4 (Oct-4) is widely regarded as a hallmark of pluripotent stem cells. The relationship of Oct-4 to pluripotent stem cells is indicated by its tightly restricted expression to undifferentiated pluripotent stem cells. Upon differentiation to somatic lineages, the expression of Oct-4 disappears rapidly. Unlike the majority of pluripotent stem cell markers, the biological role of Oct-4 has been well characterized. Studies performed in mice point to the critical role of Oct-4 in the establishment and/or maintenance of pluripotent stem cells in an uncommitted state.
抗原信息
免疫原
A synthesized peptide: human Oct 4
抗原种属
Human
基因名称
POU5F1
基因ID
蛋白名称
POU domain, class 5, transcription factor 1
Uniprot ID
功能
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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