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TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated

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货号 TMPJ-00255

别名 转化生长因子, TGF-β3, TGF-beta3, TGFB3, ARVD

TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P10600.

TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated

TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated

一键复制产品信息
Rating icon 还可以
货号 TMPJ-00255 别名 转化生长因子, TGF-β3, TGF-beta3, TGFB3, ARVD

TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P10600.

规格价格库存数量
5 μg
¥ 1,970
6-8日内发货
10 μg
¥ 3,390
6-8日内发货
20 μg
¥ 5,730
5日内发货
50 μg
¥ 9,870
5日内发货
100 μg
¥ 15,800
5日内发货
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产品介绍


生物活性
产品描述
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P10600.
生物活性
1. Measured by its ability to inhibit TGF-beta 1 activity on TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.37ng/ml. (Regularly tested) 2. Immobilized Human TGFBR2-Fc at 2μg/ml (100 μl/well)can bind Biotinylated Human TGF-beta 3-Avi . The ED50 of Biotinylated Human TGF-beta 3-Avi is 2.05 ng/ml. (Regularly tested)
研究背景
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. TGF-beta 3 binds with high affinity to TGF-beta RII, a type II serine/threonine kinase receptor. This receptor then phosphorylates and activates type I serine/threonine kinase receptors, TGF-beta RI or ALK-1, to modulate transcription through Smad phosphorylation.
种属
Human
表达系统
HEK293 Cells
标签N-Avi
蛋白编号P10600
氨基酸序列Ala301-­Ser412
蛋白构建Ala301-­Ser412 (Tyr340Phe)
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing 4 mM HCl.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名转化生长因子, TGF-β3, TGF-beta3, TGFB3, ARVD
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量10-14 KDa (reducing condition)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

计算器

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剂量转换

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