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Anti-CD122/IL2RB Antibody (8K761)
还可以产品编号 TMAY-01079
Anti-CD122/IL2RB Antibody (8K761) 是一种 Mouse 抗体，靶向 CD122/IL2RB。Anti-CD122/IL2RB Antibody (8K761) 可用于 ELISA。
Anti-CD122/IL2RB Antibody (8K761)
Anti-CD122/IL2RB Antibody (8K761)
还可以产品编号 TMAY-01079
Anti-CD122/IL2RB Antibody (8K761) 是一种 Mouse 抗体，靶向 CD122/IL2RB。Anti-CD122/IL2RB Antibody (8K761) 可用于 ELISA。
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抗原信息
| 产品描述 | Anti-CD122/IL2RB Antibody (8K761) is a Mouse antibody targeting CD122/IL2RB. Anti-CD122/IL2RB Antibody (8K761) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8K761 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-2R beta/CD122 (rh IL-2R beta/CD122; TMPY-05216; NP_000869.1; Met1-Asp239). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concerning the ability to bind interleukin 2. The low-affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high-affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high-affinity forms of CD122/IL-2RB are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. CD122/IL-2RB expression was restricted to the earliest B220+ cells (CD43+CD24-; prepro B cells; fraction A) that proliferate vigorously to IL-2 in the absence of any stromal cells, but not to IL-15. The high-affinity form of this receptor is expressed on activated T lymphocytes, activated B lymphocytes, and activated macrophages. CD122/IL-2RB plays a role in regulating normal lymphocyte development. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL-2R beta/CD122 Protein (TMPY-05216) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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