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Anti-IL1R1 Monoclonal Antibody

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产品编号 TMAZ-0067

别名 p80, Interleukin-1 receptor type I, Interleukin-1 receptor type 1, Interleukin-1 receptor alpha, CD121 antigen-like family member A

Anti-IL1R1 Monoclonal Antibody is a humanized rabbit antibody targeting IL1R1. Anti-IL1R1 Monoclonal Antibody can be used in ELISA, FCM. 可用于 ELISA,FCM。

Anti-IL1R1 Monoclonal Antibody

Anti-IL1R1 Monoclonal Antibody

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Rating icon 还可以
产品编号 TMAZ-0067 别名 p80, Interleukin-1 receptor type I, Interleukin-1 receptor type 1, Interleukin-1 receptor alpha, CD121 antigen-like family member A

Anti-IL1R1 Monoclonal Antibody is a humanized rabbit antibody targeting IL1R1. Anti-IL1R1 Monoclonal Antibody can be used in ELISA, FCM. 可用于 ELISA,FCM。

规格价格库存数量
25 μg
¥ 1,874
7日内发货
50 μg
¥ 2,248
7日内发货
100 μg
¥ 3,147
7日内发货
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产品介绍

生物活性
产品描述
Anti-IL1R1 Monoclonal Antibody is a humanized rabbit antibody targeting IL1R1. Anti-IL1R1 Monoclonal Antibody can be used in ELISA,FCM.
别名p80, Interleukin-1 receptor type I, Interleukin-1 receptor type 1, Interleukin-1 receptor alpha, CD121 antigen-like family member A
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of IL1R1 overexpressed 483F cells with TMAZ-0067, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用ELISAFCM
推荐剂量
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Single-pass membrane protein
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL1R1 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in PBS.
纯度> 95% as determined by SDS-PAGE.
研究背景Receptor for IL1A, IL1B and IL1RN (PubMed: 2950091, PubMed: 37315560). After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (PubMed: 10653850)
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin
可提供抗体种类
2
抗原信息
免疫原
IL1R1
抗原种属
Human
基因ID
3554
Uniprot ID
P14778
研究领域
Immunology Research
化学信息
分子量150 kDa
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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