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Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-DAAM1 (Thr361)。Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody 可用于 WB。
Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-DAAM1 (Thr361)。Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DAAM1 (Thr361). Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Horse,Rabbit,Sheep,GuineaPig) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Note=Perinuclear. |
| 组织特异性 | Expressed in all tissues examined. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | DAAM1 (Dishevelled associated activator of morphogenesis 1) is a diaphanous-related formin which binds to dishevelled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex assembly. It is an essential component of noncanonical Wnt signaling. DAAM1 also communicates with Rho GTPases, CIP4 and Src in the regulation of the signalling pathways that co-ordinate the dynamics of the actin filament system. DAAM1 may be a coordinator of endocytosis and cytoskeletal remodeling. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human DAAM1 around the phosphorylation site of Thr361 |
| 抗原种属 | Human |
| 基因名称 | DAAM1 |
| 基因ID | |
| 蛋白名称 | Disheveled-associated activator of morphogenesis 1 |
| Uniprot ID | |
| 功能 | Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. |
| 分子量 | Theoretical: 120-130 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |