Anti-INHBB/Activin B Antibody is a monoclonal antibody specifically targeting the inhibin subunit beta B (INHBB). The INHBB subunit homodimerizes to form Activin B, a member of the TGF-β superfamily involved in regulating cell proliferation, differentiation, apoptosis, and various pathological processes. By specifically binding to INHBB, this antibody blocks the interaction of Activin B with its receptors (e.g., ActRIIA/B and ALK4/7), thereby inhibiting the activation of the Smad2/3 signaling pathway. In experimental research, this antibody is frequently utilized to study liver fibrosis, muscle wasting (cachexia), and the progression mechanisms of various tumors.

Human

Monoclonal

Unconjugated