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Anti-INHBB/Activin B Antibody是一种针对抑制素βB亚基 (Inhibin Subunit Beta B, INHBB)的单克隆抗体。INHBB亚基通过同源二聚化形成Activin B,属于TGF-β超家族蛋白,参与调节细胞增殖、分化、凋亡及多种病理过程。Anti-INHBB/Activin B Antibody通过特异性结合INHBB,阻断Activin B与其受体的结合,从而抑制Smad2/3信号通路的激活,常用于研究肝纤维化、肌肉萎缩(恶病质)以及多种肿瘤的进展机制。
别名 抗INHBB/Activin B抗体
Anti-INHBB/Activin B Antibody是一种针对抑制素βB亚基 (Inhibin Subunit Beta B, INHBB)的单克隆抗体。INHBB亚基通过同源二聚化形成Activin B,属于TGF-β超家族蛋白,参与调节细胞增殖、分化、凋亡及多种病理过程。Anti-INHBB/Activin B Antibody通过特异性结合INHBB,阻断Activin B与其受体的结合,从而抑制Smad2/3信号通路的激活,常用于研究肝纤维化、肌肉萎缩(恶病质)以及多种肿瘤的进展机制。


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| 产品描述 | Anti-INHBB/Activin B Antibody is a monoclonal antibody specifically targeting the inhibin subunit beta B (INHBB). The INHBB subunit homodimerizes to form Activin B, a member of the TGF-β superfamily involved in regulating cell proliferation, differentiation, apoptosis, and various pathological processes. By specifically binding to INHBB, this antibody blocks the interaction of Activin B with its receptors, thereby inhibiting the activation of the Smad2/3 signaling pathway. In experimental research, this antibody is frequently utilized to study liver fibrosis, muscle wasting (cachexia), and the progression mechanisms of various tumors. |
| 别名 | 抗INHBB/Activin B抗体 |
| 反应种属 | Human |
| 应用 | ELISAFACSFunctional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | IgG1 |
| 偶联 | Unconjugated |
| Uniprot ID | |
| 靶点 | INHBB/ActivinB |
| 存储 | Store at -20°C Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 |
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