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Anti-DAPK1 Antibody (8G920)

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货号 TMAB-04976

Anti-DAPK1 Antibody (8G920) 是一种 Mouse 抗体,靶向 DAPK1。Anti-DAPK1 Antibody (8G920) 可用于 WB。

Anti-DAPK1 Antibody (8G920)

Anti-DAPK1 Antibody (8G920)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04976

Anti-DAPK1 Antibody (8G920) 是一种 Mouse 抗体,靶向 DAPK1。Anti-DAPK1 Antibody (8G920) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍


生物活性
产品描述
Anti-DAPK1 Antibody (8G920) is a Mouse antibody targeting DAPK1. Anti-DAPK1 Antibody (8G920) can be used in WB.
Ig Type
IgG2a, κ
克隆号
8G920
反应种属
Human (predicted:Mouse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm. Colocalizes with the actin filament system.
组织特异性Isoform 2 is expressed in normal intestinal tissue as well as in colorectal carcinomas.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景DAPK1 expression is frequently lost in human carcinomas and B-cell leukemia, and lower levels of expression correlates with high rates of metastasis. The loss of DAPK expression provides a link between suppression of apoptosis and metastasis. DAPK1 is thought be involved in an early apoptotic checkpoint which eliminates premalignant cells from cancer formation. Studies in bladder cancer patients have also shown that hypermethylation of DAPK1 correlates to high recurrence rates and thus DAPK1 may be used as a prognostic marker. DAPK1 is also reportedly a molecular regulator of neuronal death in epilepsy.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DAPK1
抗原种属
Human
基因名称
DAPK1
基因ID
蛋白名称
Death-associated protein kinase 1
Uniprot ID
功能
Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
化学信息
分子量Theoretical: 160 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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