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Anti-DAPK1 Antibody (8G920) 是一种 Mouse 抗体,靶向 DAPK1。Anti-DAPK1 Antibody (8G920) 可用于 WB。
Anti-DAPK1 Antibody (8G920) 是一种 Mouse 抗体,靶向 DAPK1。Anti-DAPK1 Antibody (8G920) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 |
| 产品描述 | Anti-DAPK1 Antibody (8G920) is a Mouse antibody targeting DAPK1. Anti-DAPK1 Antibody (8G920) can be used in WB. |
| Ig Type | IgG2a, κ |
| 克隆号 | 8G920 |
| 反应种属 | Human (predicted:Mouse) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cytoplasm. Colocalizes with the actin filament system. |
| 组织特异性 | Isoform 2 is expressed in normal intestinal tissue as well as in colorectal carcinomas. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | DAPK1 expression is frequently lost in human carcinomas and B-cell leukemia, and lower levels of expression correlates with high rates of metastasis. The loss of DAPK expression provides a link between suppression of apoptosis and metastasis. DAPK1 is thought be involved in an early apoptotic checkpoint which eliminates premalignant cells from cancer formation. Studies in bladder cancer patients have also shown that hypermethylation of DAPK1 correlates to high recurrence rates and thus DAPK1 may be used as a prognostic marker. DAPK1 is also reportedly a molecular regulator of neuronal death in epilepsy. |
| 免疫原 | KLH conjugated synthetic peptide: human DAPK1 |
| 抗原种属 | Human |
| 基因名称 | DAPK1 |
| 基因ID | |
| 蛋白名称 | Death-associated protein kinase 1 |
| Uniprot ID | |
| 功能 | Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis. |
| 分子量 | Theoretical: 160 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |