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Anti-DOCK2 Antibody (7U659) 是一种 Rabbit 抗体,靶向 DOCK2。Anti-DOCK2 Antibody (7U659) 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-DOCK2 Antibody (7U659) 是一种 Rabbit 抗体,靶向 DOCK2。Anti-DOCK2 Antibody (7U659) 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-DOCK2 Antibody (7U659) is a Rabbit antibody targeting DOCK2. Anti-DOCK2 Antibody (7U659) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 克隆号 | 7U659 |
| 反应种属 | Human |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Intracytoplasmic membrane. Peripheral membrane protein. Note=Colocalizes with F-actin. |
| 组织特异性 | Specifically expressed in hematopoietic cells. Highly expressed in peripheral blood leukocytes, and expressed at intermediate level in thymus and spleen. Expressed at very low level in the small intestine and colon. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2. |
| 免疫原 | A synthesized peptide: human Dedicator of cytokinesis protein 2 |
| 抗原种属 | Human |
| 基因名称 | DOCK2 |
| 基因ID | |
| 蛋白名称 | Dedicator of cytokinesis protein 2 |
| Uniprot ID | |
| 功能 | DOCK2 (dedicator of cytokinesis 2) is a hematopoietic cell-specific protein that participates in the cytoskeletal rearrangements required for lymphocyte migration in response to chemokines. DOCK2 activates the small GTPases RAC1 and RAC2 and may also be involved in IL2 transcriptional activation via the activation of RAC2. |
| 分子量 | Theoretical: 212 kDa. Actual: 212 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |