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Anti-TEM7 Antibody (4I474) 是一种 Mouse 抗体,靶向 TEM7。Anti-TEM7 Antibody (4I474) 可用于 ELISA。
Anti-TEM7 Antibody (4I474) 是一种 Mouse 抗体,靶向 TEM7。Anti-TEM7 Antibody (4I474) 可用于 ELISA。
产品描述 | Anti-TEM7 Antibody (4I474) is a Mouse antibody targeting TEM7. Anti-TEM7 Antibody (4I474) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 4I474 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TEM7/PLXDC1 (rh TEM7/PLXDC1; TMPY-02100; AAH36059.1; Met1-Thr426). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Plexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein that belongs to the plexin family. PLXDC1 / TEM3 is detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. It is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. PLXDC1 / TEM3 is not detectable in endothelial cells from normal tissue. PLXDC1 / TEM3 plays a critical role in endothelial cell capillary morphogenesis. PLXDC1 / TEM3 may play a significant role in the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). PLXDC1 / TEM3 may be a molecular target for new diagnostic and therapeutic strategies for proliferative diabetic retinopathy (PDR). PLXDC1 / TEM3 interacts with NID1. It may also interact with CTTN. |
偶联 | Unconjugated |
免疫原 | Recombinant Human TEM7/PLXDC1 Protein (TMPY-02100) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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