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Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231)
还可以产品编号 TMAH-00904
别名 Phospho-Histone H2AX (S139), p-Histone H2AX (Ser139), p-Histone H2AX (S139), Histone H2AX (p-Ser139), Histone H2AX (p-S139)
Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) 是一种抗体，靶向 Phospho-Histone H2AX (Ser139)。Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) 可用于 ELISA, WB。
Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231)
Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231)
还可以产品编号 TMAH-00904 别名 Phospho-Histone H2AX (S139), p-Histone H2AX (Ser139), p-Histone H2AX (S139), Histone H2AX (p-Ser139), Histone H2AX (p-S139)
Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) 是一种抗体，靶向 Phospho-Histone H2AX (Ser139)。Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) 可用于 ELISA, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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| 产品描述 | Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) is an antibody targeting Phospho-Histone H2AX (Ser139). Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) can be used in ELISA, WB. |
| 别名 | Phospho-Histone H2AX (S139), p-Histone H2AX (Ser139), p-Histone H2AX (S139), Histone H2AX (p-Ser139), Histone H2AX (p-S139) |
| Ig Type | Rabbit IgG |
| 克隆号 | 8H231 |
| 交叉反应 | Human |
| 验证活性 | 1. Western Blot -Positive WB detected in:293 whole cell lysate -All lanes:Phospho-Histone H2AX (S139) antibody at 0.23μg/ml -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 15 KDa -Observed band size: 15 KDa 2. IHC image of TMAH-00904 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| 应用 | ELISA, WB |
| 推荐剂量 | WB:1:3000-1:10000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Nucleus. Chromosome. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide |
| 抗原种属 | Human |
| 基因ID | 3014 |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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