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顶部生物活性储存和溶解信息计算器

Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231)

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产品编号 TMAH-00904

别名 Phospho-Histone H2AX (S139), p-Histone H2AX (Ser139), p-Histone H2AX (S139), Histone H2AX (p-Ser139), Histone H2AX (p-S139)

Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) 是一种抗体，靶向 Phospho-Histone H2AX (Ser139)。Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) 可用于 ELISA,WB。

Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231)

Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231)

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产品编号 TMAH-00904 别名 Phospho-Histone H2AX (S139), p-Histone H2AX (Ser139), p-Histone H2AX (S139), Histone H2AX (p-Ser139), Histone H2AX (p-S139)

Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) 是一种抗体，靶向 Phospho-Histone H2AX (Ser139)。Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) 可用于 ELISA,WB。

规格价格库存数量
50 μL
¥ 1,305
5日内发货
100 μL
¥ 2,195
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) is an antibody targeting Phospho-Histone H2AX (Ser139). Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) can be used in ELISA,WB.
别名Phospho-Histone H2AX (S139), p-Histone H2AX (Ser139), p-Histone H2AX (S139), Histone H2AX (p-Ser139), Histone H2AX (p-S139)
Ig Type
Rabbit IgG
克隆号
8H231
交叉反应
Human
验证活性
1. Western Blot
-Positive WB detected in:293 whole cell lysate
-All lanes:Phospho-Histone H2AX (S139) antibody at 0.23μg/ml
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 15 KDa
-Observed band size: 15 KDa
2. IHC image of TMAH-00904 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
应用ELISAWB
推荐剂量
WB:1:3000-1:10000.
抗体种类
Monoclonal
亚细胞定位Nucleus. Chromosome.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide
抗原种属
Human
基因名称
H2AFX
基因ID
3014
Uniprot ID
P16104
研究领域
Epigenetics and Nuclear Signaling
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

pHistone H2AX (Ser139)pHistone H2AX (S139)Histone H2AX (pSer139)Histone H2AX (pS139)Histone H2AX (phospho-Ser139)Histone H2AX (phospho-S139)Histone H-2AXHistone H2AXHistone H2-A.XHistone H2A.XH2AXH2AFXH2a/x

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4个月前
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