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Anti-Survivin Antibody (8S243) 是一种 Rabbit 抗体,靶向 Survivin。Anti-Survivin Antibody (8S243) 可用于 ELISA。
Anti-Survivin Antibody (8S243) 是一种 Rabbit 抗体,靶向 Survivin。Anti-Survivin Antibody (8S243) 可用于 ELISA。
产品描述 | Anti-Survivin Antibody (8S243) is a Rabbit antibody targeting Survivin. Anti-Survivin Antibody (8S243) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8S243 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Survivin/BIRC5/API4 (rh Survivin/BIRC5/API4; TMPY-03672; NP_001159.2; Met1-Asp142). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell cycle-dependently and highly expressed at mitosis. As a multitasking protein, BIRC5 has dual roles in promoting cell proliferation and preventing apoptosis. Survivin is a component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Survivin acts as an important regulator of the localization of this complex. It may counteract a default induction of apoptosis in G2/M phase. |
偶联 | Unconjugated |
免疫原 | Recombinant Human Survivin/BIRC5/API4 Protein (TMPY-03672) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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