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Anti-C5AR1 Polyclonal Antibody

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Anti-C5AR1 Polyclonal Antibody
产品编号 TMAB-00263

Anti-C5AR1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C5AR1。Anti-C5AR1 Polyclonal Antibody 可用于 WB。

Anti-C5AR1 Polyclonal Antibody

Anti-C5AR1 Polyclonal Antibody

Rating icon 还可以
Anti-C5AR1 Polyclonal Antibody
产品编号 TMAB-00263

Anti-C5AR1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C5AR1。Anti-C5AR1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-C5AR1 Polyclonal Antibody is a Rabbit antibody targeting C5AR1. Anti-C5AR1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Human (predicted:Rat,Dog,Pig,Cow,Rabbit,Sheep,GuineaPig)
验证活性
Protein: k562 (human) lysate at 40 μg;
Primary: rabbit Anti-C5R1 (TMAB-00263) at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit Igg (secondary antibody) at 1: 5000;
Predicted band size: 39 kDa
Observed band size: 36 kDa
应用
WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景CD88, also known as C5a receptor (C5aR), is a G protein-coupled integral membrane protein. CD88, which is expressed on neutrophils, monocytes, macrophages, hepatocytes and mast cells, as well as on various epithelial and endothelial cells, serves as a receptor for the inflammatory peptide C5a. Research studies suggest a role for CD88 in the inflammatory response. The binding of C5a to CD88 has been shown to elicit increased production of acute phase proteins in liver. In brain, an increased production of CD88 has been shown to be associated with inflammation. Research also indicates a role for C5a/C5aR in the pathogenesis of rheumatoid arthritis, as well as a heightened responsiveness of human bronchial epithelial cells (HBECs) to C5a upon exposure of these cells to cigarette smoke and other environmental irritants.
抗原信息
免疫原
KLH conjugated synthetic peptide: human C5R1
抗原种属
Human
基因ID
728
Uniprot ID
P21730
研究领域
MAC,Vitamins / minerals,Vitamins / Minerals,GPCR
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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