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B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (His)

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产品编号 TMPY-02031U

B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q5ZPR3-1.

B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (His)

一键复制产品信息

产品编号 TMPY-02031U

B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q5ZPR3-1.

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产品信息

生物活性	Immobilized Human B7-H3 (4Ig) , hFc Tag at 5 μg/ml (100 μl/Well) on the plate. Dose response curve for Biotinylated Anti-B7-H3 Antibody, hFc Tag with the EC50 of 44.3 ng/ml determined by ELISA.
产品描述	B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q5ZPR3-1.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q5ZPR3-1
蛋白构建	Gly27-Thr461
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	73.4 kDa (Predicted); 80-110 kDa (Due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.