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Anti-SAP/SH2D1A Antibody-HRP (9S143)

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产品编号 TMAY-01703H

Anti-SAP/SH2D1A Antibody-HRP (9S143) 是一种 HRP-conjugated Mouse 抗体,靶向 SAP/SH2D1A。Anti-SAP/SH2D1A Antibody-HRP (9S143) 可用于 ELISA。

Anti-SAP/SH2D1A Antibody-HRP (9S143)

Anti-SAP/SH2D1A Antibody-HRP (9S143)

Rating icon 还可以
产品编号 TMAY-01703H

Anti-SAP/SH2D1A Antibody-HRP (9S143) 是一种 HRP-conjugated Mouse 抗体,靶向 SAP/SH2D1A。Anti-SAP/SH2D1A Antibody-HRP (9S143) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-SAP/SH2D1A Antibody-HRP (9S143) is a HRP-conjugated Mouse antibody targeting SAP/SH2D1A. Anti-SAP/SH2D1A Antibody-HRP (9S143) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG1
克隆号
9S143
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SH2D1A ( 11149-H07ENP_002342.1Pro2-Lys97). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of a catalytic domain and the presence of an SH2domain suggest that SH2D1A regulates one or more signal transduction pathways. SH2D1A interacts with signaling lymphocytic activation molecule (SLAM), which is a transmembrane protein expressed on the surface of activated T and B cells. SH2D1A (SAP) interacts via its SH2domain with a motif (TIYXXV) present in the cytoplasmic tail of the cell-surface receptors, including CD150 / SLAM, CD84, CD229 / Ly-9, and CD244 / 2B4. SH2D1A was expressed in EBV-carrying, tumor phenotype representative (type I), but not in EBV-carrying lymphoblastoid cell line (LCL)-like (type III) or EBV-negative Burkitt lymphoma (BL) lines. It has been supposed to be related to the X-linked lymphoproliferative disease which is also known as Duncan's disease or Purtilo syndrome.
偶联与修饰
偶联
HRP
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human SH2D1A Protein (TMPY-02440)
抗原种属
Human
研究领域
Adaptor Proteins
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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