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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-Glucocorticoid Receptor (Ser226) Polyclonal Antibody

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货号 TMAB-10742

Anti-Phospho-Glucocorticoid Receptor (Ser226) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Glucocorticoid Receptor (Ser226)。Anti-Phospho-Glucocorticoid Receptor (Ser226) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-Glucocorticoid Receptor (Ser226) Polyclonal Antibody

Anti-Phospho-Glucocorticoid Receptor (Ser226) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10742

Anti-Phospho-Glucocorticoid Receptor (Ser226) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Glucocorticoid Receptor (Ser226)。Anti-Phospho-Glucocorticoid Receptor (Ser226) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Glucocorticoid Receptor (Ser226) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Glucocorticoid Receptor (Ser226). Anti-Phospho-Glucocorticoid Receptor (Ser226) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand, nuclear after ligand-binding. Isoform Beta: Nucleus. Note=Localized largely in the nucleus.
组织特异性Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocoticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human Glucocorticoid Receptor around the phosphorylation site of Ser226
抗原种属
Human
基因名称
NR3C1
基因ID
2908
蛋白名称
Glucocorticoid receptor
Uniprot ID
P04150
功能
Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.
化学信息
分子量Theoretical: 85 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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