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Anti-PCK1 Antibody (7Q973)

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Anti-PCK1 Antibody (7Q973)
产品编号 TMAC-03096
别名 Serine-protein kinase PCK1, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEPCK-C, PEPCK1, PCK1, cytosolic [GTP]

Anti-PCK1 Antibody (7Q973) 是一种 Rabbit 抗体,靶向 PCK1。Anti-PCK1 Antibody (7Q973) 可用于 ICC,IHC,WB。

Anti-PCK1 Antibody (7Q973)

Anti-PCK1 Antibody (7Q973)

Rating icon 还可以
Anti-PCK1 Antibody (7Q973)
产品编号 TMAC-03096 别名 Serine-protein kinase PCK1, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEPCK-C, PEPCK1, PCK1, cytosolic [GTP]

Anti-PCK1 Antibody (7Q973) 是一种 Rabbit 抗体,靶向 PCK1。Anti-PCK1 Antibody (7Q973) 可用于 ICC,IHC,WB。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-PCK1 Antibody (7Q973) is a Rabbit antibody targeting PCK1. Anti-PCK1 Antibody (7Q973) can be used in ICC,IHC,WB.
别名Serine-protein kinase PCK1, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEPCK-C, PEPCK1, PCK1, cytosolic [GTP]
Ig Type
IgG
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-PCK1 antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PCK1 antibody. Counter stained with hematoxylin.
3. ICC staining PCK1 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining PCK1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining PCK1 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
推荐剂量
IHC: 1:50-200; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Normal adjustment to changes in blood glucose levels depends on insulin signaling as well as enzymes involved in the regulation of gluconeogenesis. Pathological changes to this process are central to the type 2 diabetes phenotype. Phosphoenolpyruvate carboxykinase (PEPCK) plays an important role in this process by stimulating hepatic glucose production. PEPCK expression increases in response to glucagon and glucocorticoids, while insulin suppresses expression. Modulation of the signals governing PEPCK levels present a potential therapeutic approach to the treatment of insulin resistance and consequently obesity. The cytosolic form of PEPCK, known as PEPCK-C, and the mitochondrial form, known as PEPCK-M, are encoded by two different nuclear genes in mouse, human and chicken.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 69 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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