购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空

Anti-GPC3 Antibody (4L576)

Rating icon 还可以
Anti-GPC3 Antibody (4L576)
产品编号 TMAH-00502
别名 SGBS1, SGBS, SGB, SDYS, OCI-5, MXR7, GTR2-2, Glypican 3, DGSX

Anti-GPC3 Antibody (4L576) 是一种抗体,靶向 GPC3。Anti-GPC3 Antibody (4L576) 可用于 ELISA, WB, IF。

Anti-GPC3 Antibody (4L576)

Anti-GPC3 Antibody (4L576)

Rating icon 还可以
Anti-GPC3 Antibody (4L576)
产品编号 TMAH-00502 别名 SGBS1, SGBS, SGB, SDYS, OCI-5, MXR7, GTR2-2, Glypican 3, DGSX

Anti-GPC3 Antibody (4L576) 是一种抗体,靶向 GPC3。Anti-GPC3 Antibody (4L576) 可用于 ELISA, WB, IF。

规格价格库存数量
50 μL
¥ 1,305
5日内发货
100 μL
¥ 2,190
5日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载

产品介绍

生物活性
产品描述
Anti-GPC3 Antibody (4L576) is an antibody targeting GPC3. Anti-GPC3 Antibody (4L576) can be used in ELISA, WB, IF.
别名SGBS1, SGBS, SGB, SDYS, OCI-5, MXR7, GTR2-2, Glypican 3, DGSX
Ig Type
Rabbit IgG
克隆号
4L576
交叉反应
Human
验证活性
1. Western Blot
-Positive WB detected in: 293 whole cell lysate, K562 whole cell lysate
-All lanes: GPC3 antibody at 0.9μg/ml
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 66, 60, 69 KDa
-Observed band size: 66 KDa
2. Immunofluorescence staining of HepG2 cells with TMAH-00502 at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
应用
推荐剂量
WB:1:500-1:5000; IF:1:20-1:200.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Cell surface proteoglycan that bears heparan sulfate. Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation. Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligands. Positively regulates the non-canonical Wnt signaling pathway. Binds to CD81 which decreases the availability of free CD81 for binding to the transcriptional repressor HHEX, resulting in nuclear translocation of HHEX and transcriptional repression. Inhibits the dipeptidyl peptidase activity of DPP4. Plays a role in limb patterning and skeletal development by controlling the cellular response to BMP4. Modulates the effects of growth factors BMP2, BMP7 and FGF7 on renal branching morphogenesis. Required for coronary vascular development. Plays a role in regulating cell movements during gastrulation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human GPC3
抗原种属
Human
基因ID
Uniprot ID
研究领域
Stem Cells
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

Related Tags: buy Anti-GPC3 Antibody (4L576) | purchase Anti-GPC3 Antibody (4L576) | Anti-GPC3 Antibody (4L576) cost | order Anti-GPC3 Antibody (4L576)