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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GDAP1 Polyclonal Antibody

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货号 TMAB-06402

Anti-GDAP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GDAP1。Anti-GDAP1 Polyclonal Antibody 可用于 WB。

Anti-GDAP1 Polyclonal Antibody

Anti-GDAP1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06402

Anti-GDAP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GDAP1。Anti-GDAP1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-GDAP1 Polyclonal Antibody is a Rabbit antibody targeting GDAP1. Anti-GDAP1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep, Orangutan)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion outer membrane; Multi-pass membrane protein. Cytoplasm (By similarity).
组织特异性Highly expressed in whole brain and spinal cord. Predominant expression in central tissues of the nervous system not only in neurons but also in Schwann cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Glutathione S-transferases (GSTs) function to conjugate reduced glutathione to many exogenous and endogenous hydrophobic electrophiles. Although it shares the carboxy and amino-terminal glutathione S-transferase domains, GDAP1 is characterized as a GST-like protein because it contains an extended GST domain II and a predicted transmembrane domain, two characteristics which are unusual for GST family members. GDAP1 may function in a signal transduction pathway that is responsible for ganglioside-induced neurite differentiation and also may play a role in protecting myelin membranes from free-radical damage. Mutations in the gene encoding GDAP1 is the cause of many forms of Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system that is characterized by reduced nerve conduction velocities, slow progressive distal muscle atrophy and absent deep tendon reflexes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GDAP1
抗原种属
Human
基因名称
GDAP1
基因ID
54332
蛋白名称
Ganglioside-induced differentiation-associated protein 1
Uniprot ID
Q8TB36
功能
May function in a signal transduction pathway responsible for ganglioside-induced neurite differentiation. May also have a role in protecting myelin membranes against free radical-mediated damage.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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