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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HMGN3 Polyclonal Antibody

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货号 TMAB-07192

Anti-HMGN3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HMGN3。Anti-HMGN3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-HMGN3 Polyclonal Antibody

Anti-HMGN3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07192

Anti-HMGN3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HMGN3。Anti-HMGN3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-HMGN3 Polyclonal Antibody is a Rabbit antibody targeting HMGN3. Anti-HMGN3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate and uterus. Low expression in liver, spleen, placenta and ovaries.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human HMGN3
抗原种属
Human
基因名称
HMGN3
基因ID
9324
蛋白名称
High mobility group nucleosome-binding domain-containing protein 3
Uniprot ID
Q15651
功能
Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.
化学信息
分子量Theoretical: 11 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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