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Anti-TBG Antibody (7D596) 是一种 Rabbit 抗体,靶向 TBG。Anti-TBG Antibody (7D596) 可用于 ELISA。
Anti-TBG Antibody (7D596) 是一种 Rabbit 抗体,靶向 TBG。Anti-TBG Antibody (7D596) 可用于 ELISA。
产品描述 | Anti-TBG Antibody (7D596) is a Rabbit antibody targeting TBG. Anti-TBG Antibody (7D596) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7D596 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human SerpinA7 (rh SerpinA7; TMPY-01256; NP_000345.2; Met 1-Ala 415). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein that belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG binds thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3’-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 and T3, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone. |
偶联 | Unconjugated |
免疫原 | Recombinant Human SerpinA7 protein (TMPY-01256) |
抗原种属 | Human |
研究领域 | Serine Proteases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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