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Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2

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产品编号 TMAB-11071

Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-Numb (Ser276)。Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 可用于 WB。

Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2

Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-11071

Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-Numb (Ser276)。Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Numb (Ser276). Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
交叉反应
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Peripheral membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human Numb around the phosphorylation site of Ser276
抗原种属
Human
基因名称
NUMB
基因ID
蛋白名称
Protein numb homolog
Uniprot ID
功能
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
化学信息
分子量Theoretical: 70 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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