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Anti-AKR7A2 Antibody (7I916) 是一种 Mouse 抗体,靶向 AKR7A2。Anti-AKR7A2 Antibody (7I916) 可用于 WB,ICC,IHC。
Anti-AKR7A2 Antibody (7I916) 是一种 Mouse 抗体,靶向 AKR7A2。Anti-AKR7A2 Antibody (7I916) 可用于 WB,ICC,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,990 | 5日内发货 | |
100 μL | ¥ 2,980 | 5日内发货 |
产品描述 | Anti-AKR7A2 Antibody (7I916) is a Mouse antibody targeting AKR7A2. Anti-AKR7A2 Antibody (7I916) can be used in WB,ICC,IHC. |
别名 | Succinic semialdehyde reductase, SSA reductase, ARK72_HUMAN, Aldoketoreductase 7, Aldo keto reductase family 7, member A2 (aflatoxin aldehyde reductase), Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase, Aldo keto reductase family 7 member A2, Aldo keto reductase family 7, Akr7a2, AKR7, Aiar, Aflatoxin beta1 aldehyde reductase, Aflatoxin B1 aldehyde reductase member 2, Aflatoxin aldehyde reductase, AFB1AR1, AFB1-AR 1, AFB1 AR1, AFB1 aldehyde reductase 1, AFAR1, AFAR |
交叉反应 | Human,zebrafish |
验证活性 | 1. Western blot analysis of AKR7A2 on human spermatozoa lysate using anti-AKR7A2 antibody at 1/1,000 dilution. 2. ICC staining AKR7A2 in HepG2 cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:1000-2000; ICC: 1:200 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Aflatoxin B1 aldehyde reductase member 2 is an enzyme that in humans is encoded by the AKR7A2 gene. It catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate and may have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). AKR7A2 has broad substrate specificity and NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). AKR7A2 can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro) and reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It may be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. |
偶联 | Unconjugated |
免疫原 | Peptide |
Uniprot ID |
分子量 | Theoretical: 40 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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