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Anti-CYP8B1 Polyclonal Antibody
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产品编号 TMAB-00528
别名 Sterol 12-alpha-hydroxylase, Cytochrome P450, family 8, subfamily B, polypeptide 1, Cytochrome P450 8B1, CYPVIIIB1, CYP8B1, CYP12, CP8B1, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase
Anti-CYP8B1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CYP8B1。Anti-CYP8B1 Polyclonal Antibody 可用于 WB。
Anti-CYP8B1 Polyclonal Antibody
Anti-CYP8B1 Polyclonal Antibody
还可以产品编号 TMAB-00528 别名 Sterol 12-alpha-hydroxylase, Cytochrome P450, family 8, subfamily B, polypeptide 1, Cytochrome P450 8B1, CYPVIIIB1, CYP8B1, CYP12, CP8B1, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase
Anti-CYP8B1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CYP8B1。Anti-CYP8B1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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产品介绍
生物活性
抗原信息
化学信息
| 产品描述 | Anti-CYP8B1 Polyclonal Antibody is a Rabbit antibody targeting CYP8B1. Anti-CYP8B1 Polyclonal Antibody can be used in WB. |
| 别名 | Sterol 12-alpha-hydroxylase, Cytochrome P450, family 8, subfamily B, polypeptide 1, Cytochrome P450 8B1, CYPVIIIB1, CYP8B1, CYP12, CP8B1, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | Sample: Lane 1: Recombinant human CYP8B1 protein Primary: Anti-CYP8B1 (TMAB-00528) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kDa Observed band size: 55 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Endoplasmic reticulum membrane. Microsome membrane. |
| 组织特异性 | Liver. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human CYP8B1 |
| 抗原种属 | Human |
| 基因名称 | CYP8B1 |
| 基因ID | |
| 蛋白名称 | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase |
| Uniprot ID | |
| 研究领域 | Lipid metabolism,Cytochromes,Lipases,Cytochromes |
| 功能 | Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids. |
| 分子量 | Theoretical: 58 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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