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Anti-Desmocollin 2/DSC2 Antibody (7P759)

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产品编号 TMAY-01191

Anti-Desmocollin 2/DSC2 Antibody (7P759) 是一种 Rabbit 抗体,靶向 Desmocollin 2/DSC2。Anti-Desmocollin 2/DSC2 Antibody (7P759) 可用于 ELISA。

Anti-Desmocollin 2/DSC2 Antibody (7P759)

Anti-Desmocollin 2/DSC2 Antibody (7P759)

Rating icon 还可以
产品编号 TMAY-01191

Anti-Desmocollin 2/DSC2 Antibody (7P759) 是一种 Rabbit 抗体,靶向 Desmocollin 2/DSC2。Anti-Desmocollin 2/DSC2 Antibody (7P759) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-Desmocollin 2/DSC2 Antibody (7P759) is a Rabbit antibody targeting Desmocollin 2/DSC2. Anti-Desmocollin 2/DSC2 Antibody (7P759) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
7P759
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human DSC2 (rh DSC2; Q02487-1Met1-Arg684).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景DSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Like other desmocollins, murine DSC2 has two products, Dsc2a and Dsc2b, produced by alternative splicing of a 46 bp exon which encodes 11 COOH-terminal aa followed by an in-frame stop codon. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in DSC2 are associated with arrhythmogenic right ventricular dysplasia-11. DSC2 is Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. DSC2 may contribute to epidermal cell positioning by mediating differential adhesiveness between cells that express different isoforms.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human DSC2 protein
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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