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Anti-FOXO4 Antibody (2X512)

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Anti-FOXO4 Antibody (2X512)
产品编号 TMAC-01557
别名 trithorax homolog (Drosophila), translocated to 7, RGD1561201, Myeloid/lymphoid or mixed lineage leukemia, MLLT7, Mixed lineage leukemia, MGC120490, MGC117660, FOXO 4, Forkhead box O4, Fork head domain transcription factor AFX1, ALL1-fused gene from X chromosome, Afxh, AFX1, AFX

Anti-FOXO4 Antibody (2X512) 是一种 Rabbit 抗体，靶向 FOXO4。Anti-FOXO4 Antibody (2X512) 可用于 WB,IHC。

Anti-FOXO4 Antibody (2X512)

Anti-FOXO4 Antibody (2X512)

Rating icon 还可以
Anti-FOXO4 Antibody (2X512)
产品编号 TMAC-01557 别名 trithorax homolog (Drosophila), translocated to 7, RGD1561201, Myeloid/lymphoid or mixed lineage leukemia, MLLT7, Mixed lineage leukemia, MGC120490, MGC117660, FOXO 4, Forkhead box O4, Fork head domain transcription factor AFX1, ALL1-fused gene from X chromosome, Afxh, AFX1, AFX

Anti-FOXO4 Antibody (2X512) 是一种 Rabbit 抗体，靶向 FOXO4。Anti-FOXO4 Antibody (2X512) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-FOXO4 Antibody (2X512) is a Rabbit antibody targeting FOXO4. Anti-FOXO4 Antibody (2X512) can be used in WB,IHC.
别名trithorax homolog (Drosophila), translocated to 7, RGD1561201, Myeloid/lymphoid or mixed lineage leukemia, MLLT7, Mixed lineage leukemia, MGC120490, MGC117660, FOXO 4, Forkhead box O4, Fork head domain transcription factor AFX1, ALL1-fused gene from X chromosome, Afxh, AFX1, AFX
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of FOXO4 on human lung lysates using anti-FOXO4 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-FOXO4 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-FOXO4 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-FOXO4 antibody. Counter stained with hematoxylin.
应用
WB
IHC
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景FKHR (for forkhead in rhabdomyosarcoma), FKHRL1, and AFX1 are members of a subfamily of the forkhead family of transcription factors. AFX1, also known as FoxO4, is expressed in a wide variety of tissues and, like other FKHR proteins, AFX1 contains a single forkhead domain and serine-proline-rich region, which mediate DNA binding. AFX1-mediated transcriptional activation is regulated by the serine/threonine kinase Akt1, which phosphorylates AFX1 and in turn, sequesters AFX1 in the cytosol, thereby blocking nuclear localization and DNA binding. Genetic mutations in FKHR genes, including the t(2;13) and t(1;3) translocations, are commonly found in alveolar rhabdomyosarcomas. Additionally, the t(x;11) translocation of the AFX1 gene, which involves the fusion of a serine-proline-rich sequence of AFX1 to the carboxy terminus of a truncated MLL, results in acute lymphocytic leukemia.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P98177
化学信息
分子量Theoretical: 54/48 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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