购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CHRNA7 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-00430

别名 Neuronal acetylcholine receptor subunit alpha-7, NARAD, NACHRA7, NACHR alpha7, MGC120483, MGC120482, D10, D 10, CHRNA7-2, CHRNA7(cholinergic receptor nicotinic alpha 7 exons 5 10) and FAM7A(family with sequence similarity 7A exons A E) fusion, CHRNA7 FAM7A fusion protein, CHRNA7 FAM7A fusion, CHRNA7 DR1, CHRNA7, CHRFAM7A, cholinergic receptor, nicotinic, alpha 7, BTX, ALPHA-7NACHR, alpha7 nicr, ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR, ALPHA7, alpha 7 neuronal nicotinic acetylcholine receptor FAM7A hybrid, Acra7, AChR alpha 7 Receptor, ACHR ALPHA 7, ACHA7

Anti-CHRNA7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CHRNA7。Anti-CHRNA7 Polyclonal Antibody 可用于 IF,IHC-Fr,WB。

Anti-CHRNA7 Polyclonal Antibody

Anti-CHRNA7 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-00430 别名 Neuronal acetylcholine receptor subunit alpha-7, NARAD, NACHRA7, NACHR alpha7, MGC120483, MGC120482, D10, D 10, CHRNA7-2, CHRNA7(cholinergic receptor nicotinic alpha 7 exons 5 10) and FAM7A(family with sequence similarity 7A exons A E) fusion, CHRNA7 FAM7A fusion protein, CHRNA7 FAM7A fusion, CHRNA7 DR1, CHRNA7, CHRFAM7A, cholinergic receptor, nicotinic, alpha 7, BTX, ALPHA-7NACHR, alpha7 nicr, ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR, ALPHA7, alpha 7 neuronal nicotinic acetylcholine receptor FAM7A hybrid, Acra7, AChR alpha 7 Receptor, ACHR ALPHA 7, ACHA7

Anti-CHRNA7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CHRNA7。Anti-CHRNA7 Polyclonal Antibody 可用于 IF,IHC-Fr,WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-CHRNA7 Polyclonal Antibody is a Rabbit antibody targeting CHRNA7. Anti-CHRNA7 Polyclonal Antibody can be used in IF,IHC-Fr,WB.
别名Neuronal acetylcholine receptor subunit alpha-7, NARAD, NACHRA7, NACHR alpha7, MGC120483, MGC120482, D10, D 10, CHRNA7-2, CHRNA7(cholinergic receptor nicotinic alpha 7 exons 5 10) and FAM7A(family with sequence similarity 7A exons A E) fusion, CHRNA7 FAM7A fusion protein, CHRNA7 FAM7A fusion, CHRNA7 DR1, CHRNA7, CHRFAM7A, cholinergic receptor, nicotinic, alpha 7, BTX, ALPHA-7NACHR, alpha7 nicr, ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR, ALPHA7, alpha 7 neuronal nicotinic acetylcholine receptor FAM7A hybrid, Acra7, AChR alpha 7 Receptor, ACHR ALPHA 7, ACHA7
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken)
验证活性
1. Tissue/cell: human kidney tissue;4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-CHRNA7 Polyclonal Antibody, Unconjugated (TMAB-00430) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. DAPI (5 μg/ml,blue) was used to stain the cell nucleus.
2. Sample:
Lane 1: Human SH-SY5Y cell Lysates
Lane 2: Human U-87 MG cell Lysates
Lane 3: Human U251 cell Lysates
Primary: Anti-CHRNA7 (TMAB-00430) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa
3. Sample:
Lane 1: Cerebrum (Rat) Lysate at 40 μg
Lane 2: Cerebrum (Mouse) Lysate at 40 μg
Lane 3: Adrenal glands (Rat) Lysate at 40 μg
Lane 4: Adrenal glands (Mouse) Lysate at 40 μg
Lane 5: Placenta (Mouse) Lysate at 40 μg
Lane 6: Lung (Mouse) Lysate at 40 μg
Lane 7: Testis (Rat) Lysate at 40 μg
Lane 8: HepG2 (Human) Cell Lysate at 30 μg
Lane 9: SH-SY5Y (Human) Cell Lysate at 30 μg
Primary: Anti-CHRNA7 (TMAB-00430) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56/50 kDa
Observed band size: 48 kD
verifiedActivityverifiedActivityverifiedActivity
应用IFIHC-FrWB
推荐剂量
WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The Nicotinic Acetylcholine Receptors are members of a superfamily of ligand gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be hetero pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C terminal extracellular region. The Nicotinic Acetylcholine Receptor alpha 7 forms a homo oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion conducting channel across the plasma membrane.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CHRNA7
抗原种属
Human
基因名称
CHRNA7
基因ID
1139
蛋白名称
Neuronal acetylcholine receptor subunit alpha-7
Uniprot ID
Q8IUZ4
研究领域
nAch Receptors,Hypoxia,Response to hypoxia
功能
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器
Related Tags: buy Anti-CHRNA7 Polyclonal Antibody | purchase Anti-CHRNA7 Polyclonal Antibody | Anti-CHRNA7 Polyclonal Antibody cost | order Anti-CHRNA7 Polyclonal Antibody | Anti-CHRNA7 Polyclonal Antibody molecular weight