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BLM Protein, Mouse, Recombinant (His & Myc)

BLM Protein, Mouse, Recombinant (His & Myc)

产品编号 TMPH-02550
别名: BLM, Bloom syndrome protein, RecQ-like DNA helicase BLM, RECQ2, RecQ protein-like 3, RECQL3, DNA helicase, RecQ-like type 2

BLM Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.7 kDa and the accession number is O88700.

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BLM Protein, Mouse, Recombinant (His & Myc)
规格 价格/CNY 货期 数量
20 μg ¥ 1,800 20日内发货
100 μg ¥ 3,420 20日内发货
1 mg ¥ 14,600 20日内发货
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: BLM Protein, Mouse, Recombinant (His & Myc) (TMPH-02550)
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产品描述 BLM Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.7 kDa and the accession number is O88700.
种属 Mouse
表达系统 E. coli
标签 N-10xHis, C-MYC
蛋白编号 O88700
别名 BLM, Bloom syndrome protein, RecQ-like DNA helicase BLM, RECQ2, RecQ protein-like 3, RECQL3, DNA helicase, RecQ-like type 2
氨基酸序列 INAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQ
蛋白构建 684-859 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 24.7 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction. Participates in DNA replication and repair. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE). Stimulates DNA 4-way junction branch migration and DNA Holliday junction dissolution. Binds single-stranded DNA (ssDNA), forked duplex DNA and DNA Holliday junction. Recruited by the KHDC3-OOEP scaffold to DNA replication forks where it is retained by TRIM25 ubiquitination, it thereby promotes the restart of stalled replication forks.

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Keywords

BLM Protein, Mouse, Recombinant (His & Myc) BLM Bloom syndrome protein RecQ-like DNA helicase BLM RECQ2 RecQ protein-like 3 RECQL3 DNA helicase, RecQ-like type 2 recombinant recombinant-proteins proteins protein

 

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