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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PSME3 Polyclonal Antibody

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货号 TMAB-11880

Anti-PSME3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PSME3。Anti-PSME3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PSME3 Polyclonal Antibody

Anti-PSME3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11880

Anti-PSME3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PSME3。Anti-PSME3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-PSME3 Polyclonal Antibody is a Rabbit antibody targeting PSME3. Anti-PSME3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:200-500; IHC-Fr: 1:200-500; IF: 1:200-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a donut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-TP53/p53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of TP53/p53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PSME3
抗原种属
Human
基因名称
PSME3
基因ID
10197
蛋白名称
Proteasome activator complex subunit 3
Uniprot ID
P61289
功能
Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (PubMed:25361978).
化学信息
分子量Theoretical: 28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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