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Anti-PCDH8 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PCDH8。Anti-PCDH8 Polyclonal Antibody 可用于 WB。
Anti-PCDH8 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PCDH8。Anti-PCDH8 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-PCDH8 Polyclonal Antibody is a Rabbit antibody targeting PCDH8. Anti-PCDH8 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Pig,Cow,Rabbit,Goose,Sheep,Chimpanzee) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell Membrane. Single-pass type I membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH8 (protocadherin-8), also known as Arcadlin or PAPC, is a 1,070 amino acid single-pass type I membrane protein that contains six cadherin domains and belongs to the protocadherin family. Localized to the cell membrane and expressed specifically in fetal and adult brain, PCDH8 is thought to play a role in cell adhesion events in the central nervous system (CNS). PCDH8 is inactivated or silenced in breast cancer, suggesting a possible role in tumor suppression. Two isoforms of PCDH8 that differ in their cytoplasmic tails are expressed due to alternative splicing events. |
| 免疫原 | KLH conjugated synthetic peptide: human PCDH8 |
| 抗原种属 | Human |
| 基因名称 | PCDH8 |
| 基因ID | |
| 蛋白名称 | Protocadherin-8 |
| Uniprot ID | |
| 功能 | PCDH8 (Protocadherin 8) belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. It is thought to function in cell-adhesion in a calcium-dependent manner. It is predominantly expressed in brain, localizing to synaptic junctions. |
| 分子量 | Theoretical: 110 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |