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Anti-PCDH8 Polyclonal Antibody

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货号 TMAB-10052

Anti-PCDH8 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PCDH8。Anti-PCDH8 Polyclonal Antibody 可用于 WB。

Anti-PCDH8 Polyclonal Antibody

Anti-PCDH8 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10052

Anti-PCDH8 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PCDH8。Anti-PCDH8 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-PCDH8 Polyclonal Antibody is a Rabbit antibody targeting PCDH8. Anti-PCDH8 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Pig,Cow,Rabbit,Goose,Sheep,Chimpanzee)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane. Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH8 (protocadherin-8), also known as Arcadlin or PAPC, is a 1,070 amino acid single-pass type I membrane protein that contains six cadherin domains and belongs to the protocadherin family. Localized to the cell membrane and expressed specifically in fetal and adult brain, PCDH8 is thought to play a role in cell adhesion events in the central nervous system (CNS). PCDH8 is inactivated or silenced in breast cancer, suggesting a possible role in tumor suppression. Two isoforms of PCDH8 that differ in their cytoplasmic tails are expressed due to alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PCDH8
抗原种属
Human
基因名称
PCDH8
基因ID
蛋白名称
Protocadherin-8
Uniprot ID
功能
PCDH8 (Protocadherin 8) belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. It is thought to function in cell-adhesion in a calcium-dependent manner. It is predominantly expressed in brain, localizing to synaptic junctions.
化学信息
分子量Theoretical: 110 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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