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Anti-MYO7A Antibody (1Z414)
还可以产品编号 TMAH-00797
别名 USH1B, Unconventional myosin-VIIa, MYO 7A
Anti-MYO7A Antibody (1Z414) 是一种抗体，靶向 MYO7A。Anti-MYO7A Antibody (1Z414) 可用于 ELISA, FCM。
Anti-MYO7A Antibody (1Z414)
Anti-MYO7A Antibody (1Z414)
还可以产品编号 TMAH-00797 别名 USH1B, Unconventional myosin-VIIa, MYO 7A
Anti-MYO7A Antibody (1Z414) 是一种抗体，靶向 MYO7A。Anti-MYO7A Antibody (1Z414) 可用于 ELISA, FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-MYO7A Antibody (1Z414) is an antibody targeting MYO7A. Anti-MYO7A Antibody (1Z414) can be used in ELISA, FCM. |
| 别名 | USH1B, Unconventional myosin-VIIa, MYO 7A |
| Ig Type | Rabbit IgG |
| 克隆号 | 1Z414 |
| 交叉反应 | Human |
| 验证活性 | Overlay Peak curve showing HepG2 cells stained with TMAH-00797 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| 应用 | ELISA, FCM |
| 推荐剂量 | FCM:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell junction, synapse. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity. Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human MYO7A |
| 抗原种属 | Human |
| 基因ID | 4647 |
| Uniprot ID | |
| 研究领域 | Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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