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Anti-Claudin 18.2 Antibody (2E598)

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货号 TMAB-04422

Anti-Claudin 18.2 Antibody (2E598) 是一种 Rabbit 抗体，靶向 Claudin 18.2。Anti-Claudin 18.2 Antibody (2E598) 可用于 IHC-P,IHC-Fr,IF。

Anti-Claudin 18.2 Antibody (2E598)

Anti-Claudin 18.2 Antibody (2E598)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04422

Anti-Claudin 18.2 Antibody (2E598) 是一种 Rabbit 抗体，靶向 Claudin 18.2。Anti-Claudin 18.2 Antibody (2E598) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

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产品描述
Anti-Claudin 18.2 Antibody (2E598) is a Rabbit antibody targeting Claudin 18.2. Anti-Claudin 18.2 Antibody (2E598) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
2E598
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell junction > tight junction. Cell membrane.
组织特异性Concentrated at the cell-cell borders of epithelial cells.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Claudin superfamily consists of many structurally related proteins in humans (1). These proteins are important structural and functional components of tight junctions in paracellular transport (1,2). Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues (1). Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and Junction adhesion molecule (3). Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands (4). Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge (5).Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions (6).
抗原信息
免疫原
KLH conjugated synthetic peptide: human Claudin-18.2
抗原种属
Human
基因名称
CLDN18
基因ID
51208
蛋白名称
Claudin-18
Uniprot ID
P56856
功能
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
化学信息
分子量Theoretical: 28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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