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Anti-ABCG8 Polyclonal Antibody

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货号 TMAB-00026

别名 STSL, Sterolin 2, MGC142217, ATP binding cassette sub family G(WHITE) member 8(sterolin 2), ATP binding cassette sub family G member 8, ABCG8

Anti-ABCG8 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ABCG8。Anti-ABCG8 Polyclonal Antibody 可用于 ELISA,IF,IHC-Fr,IHC-P,WB。

Anti-ABCG8 Polyclonal Antibody

Anti-ABCG8 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-00026 别名 STSL, Sterolin 2, MGC142217, ATP binding cassette sub family G(WHITE) member 8(sterolin 2), ATP binding cassette sub family G member 8, ABCG8

Anti-ABCG8 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ABCG8。Anti-ABCG8 Polyclonal Antibody 可用于 ELISA,IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

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产品描述
Anti-ABCG8 Polyclonal Antibody is a Rabbit antibody targeting ABCG8. Anti-ABCG8 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
别名STSL, Sterolin 2, MGC142217, ATP binding cassette sub family G(WHITE) member 8(sterolin 2), ATP binding cassette sub family G member 8, ABCG8
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
应用ELISAIFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein (Probable).
组织特异性Strongly expressed in the liver, lower levels in the small intestine and colon. Detectable in a wide variety of human tissues.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human ABCG8
抗原种属
Human
基因名称
ABCG8
基因ID
64241
蛋白名称
ATP-binding cassette sub-family G member 8
Uniprot ID
Q9H221
研究领域
Metabolism of lipids and lipoproteins,Lipid transport,Cholesterol Metabolism,Cholesterol Metabolism,Lipid metabolism,Heart disease,Lipid metabolism
功能
Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
化学信息
分子量Theoretical: 76 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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