购物车
- 全部删除
您的购物车当前为空
Anti-GPC3 Antibody (5N458)
还可以
产品编号 TMAH-00504
别名 SGBS1, SGBS, SGB, SDYS, OCI-5, MXR7, GTR2-2, Glypican 3, DGSX
Anti-GPC3 Antibody (5N458) 是一种抗体，靶向 GPC3。Anti-GPC3 Antibody (5N458) 可用于 ELISA, FCM。
Anti-GPC3 Antibody (5N458)
Anti-GPC3 Antibody (5N458)
还可以产品编号 TMAH-00504 别名 SGBS1, SGBS, SGB, SDYS, OCI-5, MXR7, GTR2-2, Glypican 3, DGSX
Anti-GPC3 Antibody (5N458) 是一种抗体，靶向 GPC3。Anti-GPC3 Antibody (5N458) 可用于 ELISA, FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,300 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
Anti-GPC3 Antibody (5N458) 相关产品
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-GPC3 Antibody (5N458) is an antibody targeting GPC3. Anti-GPC3 Antibody (5N458) can be used in ELISA, FCM. |
| 别名 | SGBS1, SGBS, SGB, SDYS, OCI-5, MXR7, GTR2-2, Glypican 3, DGSX |
| Ig Type | Mouse IgG2a |
| 克隆号 | 5N458 |
| 交叉反应 | Human |
| 验证活性 | Overlay Peak curve showing THP-1 cells surface stained with TMAH-00504 (red line) at 1:100. Then 10% normal goat serum was Incubated to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45 min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10, 010 events was performed. |
| 应用 | |
| 推荐剂量 | FCM:1:20-1:500. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Cell surface proteoglycan that bears heparan sulfate. Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation. Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligands. Positively regulates the non-canonical Wnt signaling pathway. Binds to CD81 which decreases the availability of free CD81 for binding to the transcriptional repressor HHEX, resulting in nuclear translocation of HHEX and transcriptional repression. Inhibits the dipeptidyl peptidase activity of DPP4. Plays a role in limb patterning and skeletal development by controlling the cellular response to BMP4. Modulates the effects of growth factors BMP2, BMP7 and FGF7 on renal branching morphogenesis. Required for coronary vascular development. Plays a role in regulating cell movements during gastrulation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human GPC3 Protein |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Cancer, Developmental biology, Signal transduction, Stem cells |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
SCI 文献
评论列表
预览
Related Tags: buy Anti-GPC3 Antibody (5N458) | purchase Anti-GPC3 Antibody (5N458) | Anti-GPC3 Antibody (5N458) cost | order Anti-GPC3 Antibody (5N458)
嗨！有任何问题？点我咨询
评论内容