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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-EYA2 Antibody (9O644)

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货号 TMAB-05761

Anti-EYA2 Antibody (9O644) 是一种 Rabbit 抗体，靶向 EYA2。Anti-EYA2 Antibody (9O644) 可用于 WB。

Anti-EYA2 Antibody (9O644)

Anti-EYA2 Antibody (9O644)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05761

Anti-EYA2 Antibody (9O644) 是一种 Rabbit 抗体，靶向 EYA2。Anti-EYA2 Antibody (9O644) 可用于 WB。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-EYA2 Antibody (9O644) is a Rabbit antibody targeting EYA2. Anti-EYA2 Antibody (9O644) can be used in WB.
Ig Type
IgG
克隆号
9O644
反应种属
Human
应用WB
推荐剂量
WB: 1:1000-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性Highest expression in muscle with lower levels in kidney, placenta, pancreas, brain and heart.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5.
抗原信息
免疫原
A synthesized peptide: human EYA2
抗原种属
Human
基因名称
EYA2
基因ID
2139
蛋白名称
Eyes absent homolog 2
Uniprot ID
O00167
功能
Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1. Seems to coactivate SIX2, SIX4 and SIX5. Together with SIX1 and DACH2 seem to be involved in myogenesis. May be involved in development of the eye. Interaction with GNAZ and GNAI2 prevents nuclear translocation and transcriptional activity.
化学信息
分子量Theoretical: 59 kDa. Actual: 60 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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