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Anti-LGR-5 Antibody (8A381)
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产品编号 TMAC-02395
别名 LGR5, HG38, G-protein coupled receptor HG38, G-protein coupled receptor 67, G-protein coupled receptor 49, GPR67, GPR49
Anti-LGR-5 Antibody (8A381) 是一种 Rabbit 抗体，靶向 LGR-5。Anti-LGR-5 Antibody (8A381) 可用于 WB,IP,FCM。
Anti-LGR-5 Antibody (8A381)
Anti-LGR-5 Antibody (8A381)
还可以产品编号 TMAC-02395 别名 LGR5, HG38, G-protein coupled receptor HG38, G-protein coupled receptor 67, G-protein coupled receptor 49, GPR67, GPR49
Anti-LGR-5 Antibody (8A381) 是一种 Rabbit 抗体，靶向 LGR-5。Anti-LGR-5 Antibody (8A381) 可用于 WB,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-LGR-5 Antibody (8A381) is a Rabbit antibody targeting LGR-5. Anti-LGR-5 Antibody (8A381) can be used in WB,IP,FCM. |
| 别名 | LGR5, HG38, G-protein coupled receptor HG38, G-protein coupled receptor 67, G-protein coupled receptor 49, GPR67, GPR49 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of LGR5/GPR49 on SH-SY-5Y lysates using anti-LGR5/GPR49 antibody at 1/1,000 dilution. 2. Flow cytometric analysis of SH-SY-5Y cells with LGR5/GPR49 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors or heptahelical receptors, interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. LGR5 (leucine-rich repeat-containing G-protein coupled receptor 5), also known as GPR49 or GPR67, is a 907 amino acid multi-pass membrane protein that contains 17 leucine-rich repeats and belongs to the G protein-coupled receptor family. Expressed in placenta, skeletal muscle and spinal cord, LGR5 functions as an orphan receptor that is thought to play an important role in embryonic growth control and cellular differentiation. Overexpression of LGR5 is associated with increased tumor susceptibility and malignant transformation, implicating LGR5 as a potent tumor-inducing protein. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 100 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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