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Anti-GALNTL4 Polyclonal Antibody

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货号 TMAB-06311

Anti-GALNTL4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GALNTL4。Anti-GALNTL4 Polyclonal Antibody 可用于 WB。

Anti-GALNTL4 Polyclonal Antibody

Anti-GALNTL4 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06311

Anti-GALNTL4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GALNTL4。Anti-GALNTL4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-GALNTL4 Polyclonal Antibody is a Rabbit antibody targeting GALNTL4. Anti-GALNTL4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Golgi Apparatus membrane; Single-pass type II membrane protein
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosaminyl) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in Golgi apparatus. GalNAc-TL4, also known as LGALS14 or polypeptide GalNAc transferase-like protein 4, is a 607 amino acid single-pass type II membrane protein belonging to the glycosyltransferase 2 family and GalNAc-T subfamily. Localizing to Golgi apparatus, GalNAc-TL4 utilizes manganese and calcium as cofactors and may assist with the transfer of N-acetyl-D-galactosamine to a serine or threonine residue on protein receptors. GalNAc-TL4 likely catalyzes the initial reaction in O-linked oligosaccharide biosynthesis and contains a ricin B-type lectin domain, which binds to GalNAc and contributes to glycopeptide specificity, and two conserved domains located in the glycosyltransferase region. The N-terminal domain, also known as domain A or GT1 motif, may be involved in manganese coordination and substrate binding while the C-terminal domain, also known as domain B or Gal/GalNAc-T motif, is likely involved in catalytic reaction and UDP-Gal binding. GalNAc-TL4 exists as two alternatively spliced isoforms.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GALNTL4
抗原种属
Human
基因名称
GALNT18
基因ID
374378
蛋白名称
Polypeptide N-acetylgalactosaminyltransferase 18
Uniprot ID
Q6P9A2
功能
GALNTL4 may catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
化学信息
分子量Theoretical: 70 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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