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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-VDAC Polyclonal Antibody

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货号 TMAB-14065

Anti-VDAC Polyclonal Antibody 是一种 Rabbit 抗体，靶向 VDAC。Anti-VDAC Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-VDAC Polyclonal Antibody

Anti-VDAC Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-14065

Anti-VDAC Polyclonal Antibody 是一种 Rabbit 抗体，靶向 VDAC。Anti-VDAC Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 675
5日内发货
100 μL
¥ 975
5日内发货
500 μL
¥ 3,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-VDAC Polyclonal Antibody is a Rabbit antibody targeting VDAC. Anti-VDAC Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Endosome membrane; Peripheral membrane protein (Probable).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Voltage dependent anion selective channel protein 1 (VDAC/Porin) belongs to the eukaryotic mitochondrial porin family and forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation selective. VDAC/Porin expression is observed in the heart,liver and skeletal muscle.
抗原信息
免疫原
KLH conjugated synthetic peptide: human VDAC
抗原种属
Human
基因名称
VDAC1
基因ID
7416
蛋白名称
Voltage-dependent anion-selective channel protein 1
功能
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding.
化学信息
分子量Theoretical: 32 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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