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Anti-TNF-alpha Antibody-APC (1Q983)
还可以产品编号 TMAY-01011A
Anti-TNF-alpha Antibody-APC (1Q983) 是一种 APC-conjugated Rabbit 抗体，靶向 TNF-alpha。Anti-TNF-alpha Antibody-APC (1Q983) 可用于 FCM。
Anti-TNF-alpha Antibody-APC (1Q983)
Anti-TNF-alpha Antibody-APC (1Q983)
还可以产品编号 TMAY-01011A
Anti-TNF-alpha Antibody-APC (1Q983) 是一种 APC-conjugated Rabbit 抗体，靶向 TNF-alpha。Anti-TNF-alpha Antibody-APC (1Q983) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-TNF-alpha Antibody-APC (1Q983) is a APC-conjugated Rabbit antibody targeting TNF-alpha. Anti-TNF-alpha Antibody-APC (1Q983) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1Q983 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human TNF-α expression on human peripheral blood lymphocytes. Human peripheral blood mononulcear cells were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with APC-conjugated anti-Human TNF-α and FITC-conjugated anti-Human CD3. The dot plots were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human TNF-alpha / TNFA (rh TNF-alpha / TNFA; TMPY-00936; NP_000585.2; Val77-Leu233) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.1% sodium azide |
| 研究背景 | Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & AntibodyCancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human TNF-alpha protein (TMPY-00936) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets, Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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